Potrero Hill is a residential neighborhood in San Francisco, California. It is known for being one of the sunniest neighborhoods in the city and having view of the skyline, Sutro Tower, Twin Peaks, and the bay. A working-class neighborhood until gentrification in the late 1990s. It is now an affluent neighborhood home to some of the highest income residents …Potrero Hill is a residential neighborhood in San Francisco, California. It is known for being one of the sunniest neighborhoods in the city and having view of the skyline, Sutro Tower, Twin Peaks, and the bay. A working-class neighborhood until gentrification in the late 1990s. It is now an affluent neighborhood home to some of the highest income residents in the city according to the United States Census Bureau.