There are a group of cells dedicated to defending our bodies from all comers, these are the immune cells. Like an army, there are members that perform different tasks and that specialize in different ...

Complement component C3a is an anaphylatoxin known to induce plasma exudation and smooth muscle contraction in tissues. The effects on inflammatory effector leukocytes, however, are poorly defined and ...

Researchers in Sweden have provided a comprehensive characterization of circulating granulocytes in people infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) – the agent that ...

Basophils are a subset of granulocytes that is thought to have an important function in allergic reactions and in host defence against parasite infections. Now, Mack and colleagues have revealed that ...

The Immunologic Genome (ImmGen) Project is a consortium of immunologists and computational biologists who seek to determine the gene-expression patterns that characterize the mouse immune system ...

Two concepts are important to understanding how leukocytes become immunocompetent cells: proliferation and differentiation (Figure 6). Proliferation is the production of many cells from a single cell ...

Robert Welner, Ph.D., assistant professor in the Division of Hematology and Oncology, is the latest winner of the School of Medicine’s Featured Discovery. This initiative celebrates important research ...

Children with peanut allergy who achieved remission with sublingual immunotherapy (SLIT) had lower basophil activation before treatment and greater suppression of basophils at 1 year than those who ...

Basophils are white blood cells that the bone marrow makes. They play a role in a healthy immune system. Levels that are higher or lower than usual may be a sign of inflammation, hyperthyroidism, or ...

COVID-19 disease severity seems to be affected by the characteristics of white blood cells called granulocytes, which are part of the innate immune system. Combined measurements of granulocytes and ...