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Omega-3 fatty acids regulate mammary gland lipogenesis and development via Gαs-mediated cAMP–EPAC signaling pathway

During lactation, the mammary gland undergoes significant structural and functional changes to produce milk, which is essential for neonatal nutrition and early immune development. Traditional ...
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Bear bile powder inhibits the release of NLRP3 by activating the cAMP/PKA/CREB signaling pathway to treat dextran sulfate sodium-induced colitis in mice

BBPH, bear bile powder high dose; BBPL, bear bile powder low dose; DSS, dextran sulfate sodium; NC, normal control; 5-ASA, 5-Amino salicylic acid. Ulcerative colitis (UC) is a chronic autoimmune ...
JSTOR Daily

A broadly applicable, stress-mediated bacterial death pathway regulated by the phosphotransferase system (PTS) and the cAMP-Crp cascade

Recent work indicates that killing of bacteria by diverse antimicrobial classes can involve reactive oxygen species (ROS), as if a common, self-destructive response to antibiotics occurs. However, the ...