In biology, enzymes have evolved over millions of years to drive chemical reactions. Scientists have now derived universal rules to enable the de novo design of optimal enzymes. As an example, they ...
Biochemists from the National University of Singapore (NUS) have discovered a new subclass of trifunctional enzymes in gram-positive bacteria, which play a critical role in the biosynthesis of an ...
After completing the ancestral sequence reconstruction, the team conducted mutational experiments to see how altering the rubisco assembly, in this case breaking a hexamer into a dimer, affected the ...
Rubisco. Molecular model of the enzyme rubisco (ribulose bisphosphate carboxylase oxygenase) complexed with 2-carboxyarabinitol biphosphate. Rubisco is thought to be the most abundant and important ...
A D-dimer test is a lab test that helps diagnose blood clotting conditions. The test measures the levels of a protein fragment that remains in your blood after multiple blood clots break down. A high ...
A new study on rubisco, a photosynthetic enzyme thought to be the most abundant protein on the planet, shows that proteins can change their structural arrangement with surprising ease. The findings ...
A D-dimer test measures how much D-dimer protein is in the blood. This protein is present when blood clots break down. A typical range is 0-0.50 milligrams per liter (mg/L) of blood. D-dimer is a ...
Although D-dimer results within a typical range can rule out pulmonary embolism, high results alone can’t diagnose this condition. Doctors usually need to run extra tests to make a diagnosis. A ...
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Universal rules for designing optimal enzymes
In biology, enzymes have evolved over millions of years to drive chemical reactions. Scientists from the Max Planck Institute for Dynamics and Self-Organization (MPI-DS) now derived universal rules to ...
A new model of enzymatic reactions extends the traditional reaction coordinate by considering coupling between the enzyme and the molecule. This way, alternative ways for enzymatic reactions open ...
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