A new organoid model of the dopaminergic system sheds lights on its intricate functionality and potential implications for Parkinson's disease. The model replicates the dopaminergic system's structure ...
A new organoid model of the dopaminergic system sheds lights on its intricate functionality and potential implications for Parkinson's disease. The model, developed by the group of Jürgen Knoblich at ...
In a recent study published in Nature Neuroscience, a group of researchers explored how the cerebellum directly affects dopamine release in the substantia nigra compacta (SNc). While the cerebellum's ...
The caudate nucleus (green) is a subcortical brain region located in the striatum. The striatum is one of several neural structures that make up the basal ganglia (colored regions) located below the ...
Dopamine is known as "the reward molecule." This diagram illustrates dopaminergic neurons (i.e., dopamine-producing nerve cells) and dopaminergic pathways. Source: VectorMine/Shutterstock Motivation ...
Drug addiction poses a global public health challenge, with limited therapeutic options and modest efficacy. While clinical observations suggest that social rank plays a crucial role in determining ...
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New research has shown that Sonic Hedgehog (SHH)–Gli1 signaling in microglia amplifies inflammatory responses through the IKKβ/NF-κB pathway, contributing to dopaminergic neuron loss in Parkinson’s ...