Placing UV detectors far away from a chromatographic column can be problematic. The increased extra column volume can cause band broadening, reducing the efficiency of a separation. Also, experiments ...

The 54th International Symposium on High Performance Liquid Phase Separations and Related Techniques (HPLC 2025), was held from June 15–19, 2025, in Bruges, Belgium. This “Column Watch” installment ...

The growing demand to rapidly purify vast numbers of proteins is driving development of high-throughput, automated protein purification methods. In these automated methods, multiple channels for ...

Delivers over threefold improvements in day-to-day reproducibility 2 and decreases carryover by up to two orders of magnitude. 3 Reduces common user errors by up to 40%. 4 MILFORD, Mass., April 1, ...

A water Raman S/N ratio of at least 1,200 for the RF-20A and 2,000 for the RF-20Axs makes these detectors powerful tools for tests demanding analysis of trace-level components while retaining the ...

The Optilab ® differential refractive index (dRI) detector may be used in conjunction with any HPLC, FPLC, GPC or FFF separation system, plus a Wyatt DAWN ® or miniDAWN ® multi-angle light scattering ...

Analysts interested in organic molecules like dissolved organic matter or pharmaceuticals should consider quantifying organic molecules with the High Performance Liquid Chromatography (HPLC) ...

Default PDA instrument method settings are frequently used for routine HPLC analysis. While these default settings are often suitable, they may need to be modified to obtain optimal separations. In ...

Researchers focused on the early stages of developing innovative plant-based active ingredients for skincare, using HPLC to determine which species should be shortlisted for phytochemical profiling.

Like many other analysis platforms, HPLC was once considered a sophisticated method dominated by expert analysts or, at the very least, scientists willing to delve into an instrument’s innards. Today, ...

"The addition of the Alliance iS Bio HPLC System with PDA detection allows biopharmaceutical laboratories to perform enhanced spectral analysis, including impurity detection, peak purity analysis, ...