The Detroit Lions lost for the first time since Sept. 15 in a high-scoring affair with the Buffalo Bills in Week 15 at Ford Field in Detroit in a matchup of two of the NFL's best teams. The Lions (12-1) fell into an early two-touchdown hole and could not ...

Winning 11 straight games in the NFL — the Detroit Lions’ current streak — is pretty rare. But winning 12 straight, as the Lions could do on Sunday with a victory over the Buffalo Bills at Ford Field (4:25 p.m., CBS)? That’s elite territory ...

Detroit — The Buffalo Bills defeated the Detroit Lions 48-42 Sunday at Ford Field in Detroit. This game was an offensive battle from start to finish. The teams combined for 1088 yards of offense ...

The Bills improved to 11-3, two games behind the Kansas City Chiefs in the AFC with three games remaining, and took a one-game lead over Pittsburgh for the conference’s second seed.

but he’s a powerful edge-setter against the run and the Lions must make the Bills one-dimensional on offense by stopping James Cook and the running game. Buffalo averages 6.47 yards per carry ...

Kickoff is on Sunday, Dec. 15, at 4:25 p.m. ET on CBS. The Detroit Lions will host the Buffalo Bills at Ford Field for a highly anticipated game.

Here’s the preview, odds, best bets, and expert predictions for the upcoming Buffalo Bills vs. Detroit Lions game.

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