Injuries already are accruing across the NFL, knocking several star players out and forcing teams to turn to backups and ...

The 49ers are partly to blame for why Christian McCaffrey will be out at least four games and possibly more as he nurses ...

No Kittle means the 49ers will be down three All-Pros on offense. The club figured to rely heavily on him while McCaffrey and ...

The Rams have their work cut out for them in Week 3 but they have a chance to upset the 49ers if they win these 5 matchups ...

Matthew Berry breaks down his Love/Hate players for Week 3 and explains to fantasy managers why their seasons aren't over ...

George Kittle missed practice on Thursday because of a hamstring injury. Here's the latest on the TE's status for the Week 3 ...

Injuries can make or break your fantasy season. Here is the latest news on the NFL's biggest stars with injury questions ...

Just as the San Francisco 49ers won’t miss seeing Aaron Donald lining up for the Los Angeles Rams on Sunday, Sean McVay won’t ...

The San Francisco 49ers and Miami Dolphins are two teams with very different needs, and one NFL insider believes ...

San Francisco 49ers left tackle Trent Williams found a possible silver lining in all the injuries the team is dealing with ...

The San Francisco 49ers will be missing two of their biggest playmakers when they visit SoFi Stadium on Sunday to face the ...

Injuries have caused many problems for the San Francisco 49ers this year, and now Brock Purdy has lost another offensive ...