Perforin forms transmembrane pores in the plasma membrane, allowing granzymes to enter the target cell cytosol and trigger ...

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Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. The complement system and neutrophils ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Aggressive prostate cancer (PCa) variants ...

Oncolytic adenoviruses were designed to reach potent intratumoral T-cell activation via expression of bifunctional-T-cell ...

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Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. TFs are key components of gene regulatory ...

Intracellular lipid transport can occur by flip‐flop from one side of a bilayer to the other, by vesicular trafficking, by lipid transfer proteins, or by diffusion within a bilayer 34. MAMs are hubs ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Single cells are typically typed by clustering ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. The ESCRT machinery mediates membrane ...