Mitochondria are cell organelles surrounded by a double membrane. In addition to numerous essential functions in the ...

Mitochondria are cell organelles surrounded by a double membrane. In addition to numerous essential functions in the metabolism of the cell, they also play a key role in the integration of signals ...

This paper presents an effort to realize a stator with a direct cooling coil structure as a solution for a drive motor in the trend to promote electrification of automobiles. A channel made of high ...

Sleep stage dynamics can be adequately represented using Markov chain models to improve classification accuracy. The present study proposes a new post-processing method based on channel fusion using ...

Here, we review the structure and function of ABC proteins and discuss SUR, its regulation of the K ATP channel, and its role in cardiovascular disease. ATP-binding cassette (ABC) proteins constitute ...

The kinesin spindle protein (KSP) is a mitotic kinesin involved in the establishment of a functional bipolar mitotic spindle during cell division. It is considered to be an attractive target for ...

Although the genes encoding the components of the ATP synthase operon are downregulated by decreased metabolic and replication requirements, this enzyme still represents a sensitive drug target.

The same diversity in the atpE gene which explains natural and acquired resistance to TMC207 seems to justify the low affinity of the drug to mitochondrial ATP synthase; a methionine at position ...

Sequence requirements of the ATP-binding site within the C-terminal nucleotide-binding domain (NBD2) of mouse P-glycoprotein were investigated by using two recombinantly expressed soluble proteins ...